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Liver function in workers exposed of the cosmetics industry
T Casale1, T Caciari, M V Rosati
1Department of Anatomy, Histology, Medical-Legal and the Orthopedics, Unit of Occupational Medicine, Sapienza University of Rome, Italy.
Annali Di Igiene : Medicina Preventiva E Di Comunita
|November 29, 2013
Summary
Occupational exposure to cosmetic factory substances may affect liver function. Workers showed higher levels of liver enzymes and total bilirubin, indicating potential health risks.
Area of Science:
- Occupational Health
- Toxicology
- Biochemistry
Background:
- Cosmetic industry workers may face occupational exposure to various chemical substances.
- Potential health effects of these exposures on liver function and blood parameters are not fully understood.
Purpose of the Study:
- To investigate the association between occupational exposure in cosmetic factories and alterations in liver function tests and blood counts.
- To compare biochemical and hematological parameters between exposed workers and unexposed controls.
Main Methods:
- A case-control study involving 48 exposed cosmetic workers and 86 unexposed controls.
- Comprehensive blood tests including complete blood count, liver function tests (bilirubin, transaminases, alkaline phosphatase), and cholinesterase.
- Statistical analysis using Student's t-test and chi-square test to compare groups.
Main Results:
- 35.4% of cosmetic industry workers exhibited abnormal liver test values.
- A statistically significant higher prevalence of elevated GPT (alanine aminotransferase) and total bilirubin was observed in exposed workers compared to controls (p <0.05).
Conclusions:
- Occupational exposure to substances in the cosmetic industry can impact liver function.
- Even low-dose exposures may lead to measurable changes in specific liver parameters among exposed workers.
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