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Management of the ACC/AHA Stage D patient: cardiac transplantation

Michelle M Kittleson1, Jon A Kobashigawa

  • 1Division of Cardiology, Cedars-Sinai Heart Institute, Los Angeles, CA, USA.

Cardiology Clinics
|November 30, 2013
PubMed

Insights

Cardiac transplantation is a key therapy for end-stage heart disease when other treatments fail. This overview covers heart transplant evaluation, physiology, immunosuppression, and complications.

Area of Science:

  • Cardiology
  • Transplant Surgery

Background:

  • Cardiac transplantation has evolved over 40 years.
  • It is the preferred therapy for select patients with end-stage heart disease.

Purpose of the Study:

  • To provide an overview of heart transplantation in the current era.
  • Focus on evaluation, physiology, immunosuppression, and complications.

Main Methods:

  • Review of current practices in heart transplantation.
  • Focus on patient selection criteria.
  • Discussion of post-transplant management.

Main Results:

  • Heart transplantation is indicated for refractory heart failure, angina, or arrhythmias.
  • The article details the physiological changes in a transplanted heart.
  • Covers early and long-term complications.

Conclusions:

  • Cardiac transplantation remains a vital treatment option for advanced heart failure.
  • Understanding the comprehensive aspects of heart transplantation is crucial for patient outcomes.

Keywords:
Cardiac transplantationEnd-stage heart failureImmunosuppressionRejection

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