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The office visit.

Ryan P Smith1, Robert M Coward, Larry I Lipshultz

  • 1Department of Urology, University of Virginia, PO Box 800422, Charlottesville, VA 22908, USA.

The Urologic Clinics of North America
|November 30, 2013
PubMed
Summary
This summary is machine-generated.

This review covers current male infertility evaluations, emphasizing history, physical exams, and semen analysis. Future diagnostic approaches incorporating advanced tests like DNA fragmentation and genetic analysis are also explored.

Keywords:
Assisted reproductive technologyMale infertilityMen’s healthSemen analysis

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Area of Science:

  • Reproductive Medicine
  • Urology
  • Andrology

Background:

  • Male infertility affects a significant portion of couples seeking fertility treatment.
  • Current diagnostic paradigms rely heavily on traditional methods.
  • Emerging technologies offer potential for more precise etiological diagnosis.

Purpose of the Study:

  • To summarize the current office-based evaluation of male infertility.
  • To discuss advancements in diagnostic assessments.
  • To speculate on the future evolution of male infertility evaluations.

Main Methods:

  • Comprehensive review of current literature and clinical practices.
  • Discussion of traditional diagnostic tools: history, physical examination, and semen analysis.
  • Exploration of adjunctive assessments: reactive oxygen species, DNA fragmentation, and fluorescent in situ hybridization (FISH).

Main Results:

  • Routine semen analysis remains a cornerstone of male infertility assessment.
  • Advanced techniques like DNA fragmentation and FISH provide deeper insights into sperm function and genetics.
  • Analysis of genetic and endocrine abnormalities is crucial for a complete evaluation.

Conclusions:

  • The evaluation of male infertility is evolving with new diagnostic technologies.
  • A combination of traditional and advanced methods will likely shape future diagnostic algorithms.
  • Personalized approaches based on comprehensive testing will improve male infertility management.