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Updated: May 5, 2026

Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research
Published on: October 22, 2014
Effect of shisha vs. cigarette smoking on endothelial function by brachial artery duplex ultrasonography: an
Ghada M Selim1, Remon Z Elia, Ayman S El Bohey
1Department of Cardiology and Radiodiagnosis, Faculty of Medicine, Ain Shams University, Cairo-Egypt. Ghadaselim23@yahoo.com.
Objective:
In this study, we sought to investigate the effect of shisha smoking on endothelial function compared to cigarettes, using brachial artery ultrasound (BAUS) imaging in asymptomatic young adults with no other cardiovascular risk factors.
Methods:
This is an observational case-control study where 30 young shisha smokers, 30 cigarette smokers and 10 healthy, non-smokers, age- matched subjects between 25-35 years old with no cardiovascular risk factors were recruited from all around Egypt. Flow-mediated dilation was assessed using brachial artery duplex ultrasonography.
Results:
FMD% was significantly impaired among shisha smokers compared to cigarette smokers and non-smokers cigarettes (7.9 ± 3.8% vs. 12 ± 3.4% and 21.5 ± 2.5% respectively p<0.001).
Conclusion:
Shisha smoking has a more hazardous effect on brachial artery endothelial- dependent flow mediated vasodilation compared to cigarette.

