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Updated: May 5, 2026

Three-dimensional Imaging of Nociceptive Intraepidermal Nerve Fibers in Human Skin Biopsies
Published on: April 29, 2013
Neuroimaging of neurocutaneous diseases
Kaveer Nandigam1, Laszlo L Mechtler, James G Smirniotopoulos
1Neurology and Stroke Associates, 640 E Oregon Rd, Lititz, Lancaster, PA, USA; Dent Neurological Institute, Buffalo, NY, USA.
Abstract:
An in-depth knowledge of the imaging characteristics of the common neurocutaneous diseases (NCD) described in this article will help neurologists understand the screening imaging modalities in these patients. The future of neuroimaging is geared towards developing and refining magnetic resonance imaging (MRI) sequences. The detection of tumors in NCD has greatly improved with availability of high-field strength 3T MRI machines. Neuroimaging will remain at the heart and soul of the multidisciplinary care of such complex diagnoses to guide early detection and monitor treatment.
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