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Irritation and staining by 10-butyryl dithranol (butantrone) in psoriasis
Abstract:
An open clinical trial was carried out using butantrone ointment in the treatment of 10 patients with psoriasis in order to assess staining and irritation in relation to efficacy. At 0.5% and 1.0% strengths, butantrone produced significant levels of irritation and staining with minimal clinical response and poor patient compliance.