Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

106
Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within...
106
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

150
Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
150
Mechanism of Antibiotic Resistance in MRSA01:25

Mechanism of Antibiotic Resistance in MRSA

245
Antibiotic resistance in bacteria arises when microorganisms evolve the ability to withstand drugs designed to kill them or inhibit their growth, rendering once-effective treatments useless. This phenomenon, driven by genetic change and selection under antibiotic exposure, poses a profound threat to modern medicine. Mechanisms include drug-inactivating enzymes (e.g., β-lactamases), efflux pumps that eject antibiotics, mutations altering antibiotic targets, decreased drug uptake, and...
245
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

4.7K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
4.7K
Transmission-based Precautions I: Contact, Enteric, and Droplets01:17

Transmission-based Precautions I: Contact, Enteric, and Droplets

5.1K
Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
5.1K
Defense Against Bacterial Pathogens01:31

Defense Against Bacterial Pathogens

3.1K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
3.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Experiences of Residents and Fellows at Mayo Clinic After the Rapid Implementation of Telemedicine During the COVID-19 Pandemic.

Journal of medical education and curricular development·2024
Same author

Utilization and Outcomes of Multigene Panel Testing in Patients With Pancreatic Ductal Adenocarcinoma.

JCO oncology practice·2024
Same author

Do physicians know when to refer patients for genetic testing?

Journal of genetic counseling·2023
Same author

More Than Skin Deep: Dermatologic Conditions in Athletes.

Sports health·2022
Same author

Celiac disease.

American family physician·2008
Same author

Henoch-Schönlein purpura: a review article.

Southern medical journal·2007

Related Experiment Video

Updated: May 5, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA

Published on: February 9, 2011

22.2K

A practical guide to community-acquired MRSA.

Aristides Sastre1, Paul F Roberts, R John Presutti

  • 1Department of Family Medicine, Mayo Clinic, Jacksonville, FL, USA.

The Journal of Family Practice
|November 30, 2013
PubMed
Summary
This summary is machine-generated.

Community-associated Methicillin-Resistant Staphylococcus aureus (CA-MRSA) skin infections are increasing. Identifying high-risk patients and effective evidence-based treatments is crucial for managing these infections.

More Related Videos

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat
07:46

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat

Published on: June 4, 2012

17.1K
Multiplex PCR Assay for Typing of Staphylococcal Cassette Chromosome Mec Types I to V in Methicillin-resistant Staphylococcus aureus
09:03

Multiplex PCR Assay for Typing of Staphylococcal Cassette Chromosome Mec Types I to V in Methicillin-resistant Staphylococcus aureus

Published on: September 5, 2013

11.4K

Related Experiment Videos

Last Updated: May 5, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA

Published on: February 9, 2011

22.2K
Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat
07:46

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat

Published on: June 4, 2012

17.1K
Multiplex PCR Assay for Typing of Staphylococcal Cassette Chromosome Mec Types I to V in Methicillin-resistant Staphylococcus aureus
09:03

Multiplex PCR Assay for Typing of Staphylococcal Cassette Chromosome Mec Types I to V in Methicillin-resistant Staphylococcus aureus

Published on: September 5, 2013

11.4K

Area of Science:

  • Infectious Diseases
  • Dermatology
  • Public Health

Background:

  • Rising incidence of community-associated Methicillin-Resistant Staphylococcus aureus (CA-MRSA) skin and soft tissue infections (SSTIs).
  • Need for clear identification of patient risk factors.
  • Importance of evidence-based treatment protocols for CA-MRSA SSTIs.

Purpose of the Study:

  • To identify patient populations at higher risk for CA-MRSA SSTIs.
  • To review and summarize current evidence-based treatment guidelines for CA-MRSA SSTIs.

Main Methods:

  • Systematic review of epidemiological data on CA-MRSA SSTIs.
  • Analysis of clinical studies evaluating risk factors.
  • Literature review of treatment efficacy and guidelines.

Main Results:

  • Key risk factors for CA-MRSA SSTIs identified (e.g., close contact, certain activities).
  • Effective antibiotic and non-antibiotic treatment options outlined.
  • Treatment recommendations based on infection severity and patient factors.

Conclusions:

  • Proactive identification of at-risk individuals is essential.
  • Adherence to evidence-based protocols improves patient outcomes for CA-MRSA SSTIs.
  • Ongoing surveillance and guideline updates are necessary.