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Earigate™ for softening ear wax: is it safe when the eardrum is perforated?
Olubunmi V Akinpelu1, Cathy Lemieux1, Dan Citra1
1McGill Auditory Sciences Laboratory, Montreal Children's Hospital, Montreal, Quebec, Canada.
International Journal of Pediatric Otorhinolaryngology
|December 3, 2013
Summary
Earigate™ was tested for safety as an ear wax softener. This animal study found no evidence of hearing damage, indicating Earigate™ is safe for ear wax removal.
Area of Science:
- Otolaryngology
- Pharmacology
Background:
- Earwax impaction is a common condition.
- Current treatments for earwax removal may have varying safety profiles.
Purpose of the Study:
- To evaluate the safety and potential ototoxicity of Earigate™.
- To assess Earigate™ as a potential earwax softening product.
Main Methods:
- A prospective, controlled animal study was conducted.
- Chinchillas underwent bilateral myringotomies, with Earigate™ applied to one ear canal.
- Auditory brainstem response (ABR) was used to assess hearing thresholds before and after application.
Main Results:
- No statistically significant differences in mean hearing threshold shifts were observed between the Earigate™-treated ears and control ears.
- Hearing assessments at 3 and 10 days post-application showed comparable results across all frequencies.
- The results indicate no ototoxic effects from Earigate™ administration.
Conclusions:
- Earigate™ administration did not induce ototoxicity in chinchillas as measured by ABR.
- The findings support the safety of Earigate™ for use as an ear wax softening agent.
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