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Synthesis, anti-HIV activity, integrase enzyme inhibition and molecular modeling of catechol, hydroquinone and quinol

Rohan Pawar1, Tiyasa Das2, Sanjay Mishra1

  • 1Laboratory for Advanced Research in Natural and Synthetic Chemistry, V.G. Vaze College, Mumbai University, Mithagar Road, Mulund (East), Mumbai 400 081, India.

Bioorganic & Medicinal Chemistry Letters
|December 3, 2013
PubMed

Keywords:
3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromideACNAnti-HIV-1 activityComputational studyDiels–Alder reactionHIV-1 integrase inhibitionIBDIN CCDLabdane analogsMTTRTTIacetonitrileintegrase catalytic core domainiodoso benzene diacetateo-Quinol–catechol–hydroquinone moietyroom temperaturetherapeutic index

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