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Posterior reversible encephalopathy syndrome due to pulse methylprednisolone therapy in a child
Faruk İncecik1, M Özlem Hergüner, Dinçer Yıldızdaş
1Division of Pediatric Neurology, Department of Pediatrics, Çukurova University Faculty of Medicine, Adana, Turkey. fincecik@yahoo.com.
Insights
Posterior reversible encephalopathy syndrome (PRES) is a neurological condition. This case study highlights PRES as a complication of pulse methylprednisolone therapy in an eight-year-old boy.
Area of Science:
- Neurology
- Radiology
- Pediatrics
Background:
- Posterior reversible encephalopathy syndrome (PRES) is a neurological disorder characterized by specific radiological findings.
- PRES is associated with various conditions including medications, renal disease, autoimmune disorders, transplantation, and sepsis in children.
Observation:
- This report details an eight-year-old boy diagnosed with PRES.
- The patient experienced PRES during pulse methylprednisolone therapy.
Findings:
- PRES is identified as a neurological complication linked to pulse methylprednisolone treatment.
- The condition demonstrated a positive response to immediate cessation of the therapy and management of blood pressure.
Implications:
- Early recognition and management of PRES are crucial for favorable outcomes.
- This case underscores the importance of monitoring for PRES in pediatric patients receiving pulse methylprednisolone therapy.
Abstract:
Posterior reversible leukoencephalopathy syndrome (PRES) is a recently described disorder with typical radiological findings of bilateral grey and white matter abnormalities in the posterior regions of the cerebral hemispheres. It has been described in children in association with some medications, renal disease, autoimmune disease, transplantation, and sepsis. In this report, we discuss an eight-year-old boy with PRES during pulse methylprednisolone therapy. In conclusion, PRES is a neurological complication of pulse methylprednisolone therapy, which responds favorably to prompt therapy withdrawal and blood pressure control.
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