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Updated: May 5, 2026

Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry
Published on: January 19, 2020
A novel laboratory approach for the demonstration of hemodynamic principles: the arterial blood flow reflection
Marina Djelić1, Sanja Mazić, Dejan Žikić
1Department of Medical Physiology, School of Medicine, University of Belgrade, Serbia; and.
Abstract:
In the frame of a laboratory training course for medicine students, a new approach for laboratory exercises has been applied to teach the phenomena of circulation. The exercise program included measurements of radial artery blood flow waveform for different age groups using a noninvasive optical sensor. Arterial wave reflection was identified by measurements of blood flow waveforms before and after arterial branching. Students were able to distinguish between different waveforms of blood flow within different age groups. Furthermore, students were given the opportunity to explore the effect of aging on the elasticity of blood vessels. This exercise is an introduction to the fundamental physical laws of hemodynamics that can facilitate the learning and understanding of cardiovascular physiology to students of medicine.
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