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Updated: May 5, 2026

Extraction and Purification of Polyphenols from Freeze-dried Berry Powder for the Treatment of Vascular Smooth Muscle Cells In Vitro
Published on: July 5, 2017
Polyphenols: a nutraceutical approach against diseases
Andréa P B Gollucke, Rogério C Peres, Odair A
1HEXALAB/UNISANTOS - Catholic University of Santos. Av. Conselheiro Nebias, 300. Santos-SP 11015-002. Brazil. gollucke@uol.com.br.
Grape polyphenols combat diseases linked to oxidative stress. New nutraceuticals rich in these compounds offer targeted prevention and treatment for specific health conditions.
Area of Science:
- Food Science
- Biochemistry
- Nutraceuticals
Background:
- Polyphenols are natural compounds found abundantly in red grapes and other food sources.
- These compounds are recognized for their potential role in preventing diseases associated with oxidative stress.
Purpose of the Study:
- To review the protective effects of grape polyphenols against various diseases.
- To discuss novel polyphenol-rich nutraceutical products designed for disease prevention and treatment.
Main Methods:
- Literature review focusing on the biological actions of grape polyphenols.
- Analysis of recent patents related to polyphenol applications in health.
Main Results:
- Grape polyphenols exhibit beneficial effects including maintaining endothelial function, enhancing antioxidant capacity, and protecting against low-density lipoprotein (LDL) oxidation.
- Recent innovations in polyphenol-based nutraceuticals indicate a trend towards targeted therapeutic approaches.
Conclusions:
- Grape polyphenols possess significant health-promoting properties relevant to combating oxidative stress-related diseases.
- The development of specialized polyphenol-rich nutraceuticals represents a promising strategy for disease prevention and management.
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