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Updated: May 5, 2026
Live-cell Imaging of Lysosomal Membrane Permeabilization During Necroptosis
Published on: November 14, 2025
Fluorescence imaging lysosomal changes during cell division and apoptosis observed using Nile Blue based
Jiangli Fan1, Huijuan Dong, Mingming Hu
1State Key Laboratory of Fine Chemicals, Dalian University of Technology, No. 2 Linggong Road, High-tech District, Dalian 116024, China. fanjl@dlut.edu.cn pengxj@dlut.edu.cn.
Abstract:
, a Nile Blue based NIR fluorescent dye was reported. is highly effective in specifically labeling lysosomes with low concentration and good photostability in various kinds of live cells. It was first successfully used to observe the disappearance and reproduction of lysosomes during cell division.
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