Related Experiment Video
Updated: May 5, 2026

12:28
Designing a Bioreactor to Improve Data Acquisition and Model Throughput of Engineered Cardiac Tissues
Published on: June 2, 2023
3.6K
[Designing special prosthesis "spacer"]
Jovan Grujić1, Slobodan Tabaković, Milan Zeljković
1DOO Grujic & Grujić, Novi Sad, Srbija.
Acta Chirurgica Iugoslavica
|December 5, 2013
Summary
This study details the creation of custom "Spacer" endoprostheses for treating malignant bone diseases. Advanced computer modeling ensures precise fit and load transfer for improved patient outcomes.
Area of Science:
- Orthopedic Surgery
- Biomedical Engineering
- Oncology
Background:
- Malignant bone diseases affecting the femur, humerus, and tibia require innovative treatment strategies.
- Traditional prostheses may not adequately address the complex geometry and load-bearing requirements in these cases.
Purpose of the Study:
- To describe the design and computer-aided manufacturing process for specialized "Spacer" endoprostheses.
- To enable precise surgical removal of diseased bone and accurate fitting of custom implants.
Main Methods:
- Utilizing diagnostic imaging (X-ray, CT, MRI) to create detailed 3D computer models of bone geometry.
- Translating 2D image pixels into 3D voxels for comprehensive geometric analysis.
- Developing specialized software for prosthesis design based on patient-specific bone dimensions and disease extent.
Main Results:
- The "Spacer" prosthesis design features proximal and distal components connected by screws, allowing linear load transfer without screw stress.
- Accurate determination of bone resection margins and medullary canal space for optimal implant integration.
- Computer modeling facilitates precise sizing and implementation of the custom endoprosthesis.
Conclusions:
- Custom "Spacer" endoprostheses, designed via advanced computer modeling, offer a viable solution for malignant bone tumor treatment.
- This approach ensures accurate implant fit, preserves bone structure, and facilitates load transfer, potentially improving functional recovery.

