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Predictive value of echocardiography-derived arterial compliance for increased arterial stiffness in hypertensive

Levent Korkmaz1, Omer F Cirakoglu, Mustafa T Ağaç

  • 1aDepartment of Cardiology, Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital bDepartment of Radiology, Akcaabat State Hospital, Trabzon cDepartment of Cardiology, Adana Numune Training and Research Hospital, Adana, Turkey.

Blood Pressure Monitoring
|December 5, 2013
PubMed

Insights

Echocardiography-derived arterial compliance (AC) is a predictor of arterial stiffness in hypertensive patients. Lower AC values indicate increased arterial stiffness, identified by the cardio-ankle vascular index (CAVI).

Area of Science:

  • Cardiovascular Medicine
  • Vascular Biology
  • Diagnostic Imaging

Background:

  • Increased arterial stiffness is a significant predictor of cardiovascular events.
  • The cardio-ankle vascular index (CAVI) is a validated measure of arterial stiffness.
  • Arterial compliance (AC) can be estimated using the stroke volume (SV) to pulse pressure (PP) ratio.

Purpose of the Study:

  • To investigate the association between echocardiography-derived arterial compliance (AC) and arterial stiffness measured by CAVI.
  • To determine if AC is an independent predictor of increased arterial stiffness in hypertensive individuals.

Main Methods:

  • One hundred forty asymptomatic hypertensive patients were enrolled.
  • Arterial compliance index (SV/PPi) was calculated from echocardiography data.
  • Arterial stiffness was assessed using the VaSera-1000 CAVI instrument.

Main Results:

  • A statistically significant negative correlation was found between SV/PPi and CAVI (r=-0.402; P<0.001).
  • SV/PPi was identified as an independent predictor of increased CAVI (CAVI≥9) (95% CI: 0.001-0.147; P<0.001).
  • Lower SV/PPi values were observed in patients with abnormal CAVI (≥9) compared to those with normal or borderline CAVI (<9) (0.68±0.23 vs. 0.93±0.27; P<0.001).

Conclusions:

  • Echocardiography-derived arterial compliance (AC) assessment may offer valuable predictive information regarding increased arterial stiffness.
  • This non-invasive method could aid in identifying asymptomatic hypertensive patients at higher cardiovascular risk.
Abstract

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