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Trial-based clinical and economic analyses: the unhelpful quest for conformity
David G T Whitehurst1, Stirling Bryan
1Faculty of Health Sciences, Blusson Hall 10504, Simon Fraser University, 8888 University Drive, Burnaby, British Columbia V5A 1S6, Canada. david_whitehurst@sfu.ca.
Trials
|December 7, 2013
Summary
Clinical and economic research findings often align, but sometimes appear contradictory. This commentary questions whether clinical and economic evaluations must always be compatible in healthcare decision-making.
Area of Science:
- Health Economics
- Clinical Research
- Decision Analysis
Background:
- Clinical and economic research frequently inform healthcare decisions.
- Apparent contradictions between clinical and economic findings can cause unease.
- Economic evaluations play an increasing role in healthcare policy.
Purpose of the Study:
- To challenge the assumption that clinical and economic evaluations must be compatible.
- To explore the implications of potential discordance between clinical and economic research.
Main Methods:
- This is a commentary, not an empirical study.
- It involves critical analysis of the relationship between clinical and economic research paradigms.
- Discussion of existing literature and theoretical frameworks.
Main Results:
- Conformity between clinical and economic research findings is not always present.
- Apparent contradictions do not necessarily invalidate either type of evaluation.
- The necessity of strict compatibility is questioned.
Conclusions:
- Healthcare decision-making can accommodate non-compatible clinical and economic evaluations.
- Focusing solely on compatibility may overlook valuable insights from economic evaluations.
- Further discussion is needed on integrating potentially divergent findings.
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