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Oral immunization of mice with lily pollen expressing HBsAg
Hee-Sung Park1, Eun-Hye Park, Young-Joo Heo
1Department of Biotechnology, Catholic University of Daegu.
Bioscience, Biotechnology, and Biochemistry
|December 10, 2013
Abstract:
Lily pollen was developed to express HBsAg by Agrobacterium-mediated transformation. A double prime-boost strategy combining parenteral and oral HBsAg boosters was found to increase antibody titer levels 10-fold, as compared to a single process of priming and boosting. Lily pollen may prove a tool for oral vaccine development.
