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Gestational weight gain in relation to offspring obesity over the life course: a systematic review and bias-adjusted

A A Mamun1, M Mannan, S A R Doi

  • 1School of Population Health, University of Queensland, Brisbane, Australia.

Obesity Reviews : an Official Journal of the International Association for the Study of Obesity
|December 11, 2013
PubMed

Insights

Maternal gestational weight gain (GWG) impacts offspring obesity risk. Inadequate GWG decreased risk, while excess GWG increased offspring obesity risk across all life stages.

Area of Science:

  • Reproductive Health
  • Pediatric Health
  • Public Health

Background:

  • Gestational weight gain (GWG) is a known risk factor for childhood obesity.
  • The long-term effects of maternal GWG on offspring obesity across different life stages are not well-established.

Purpose of the Study:

  • To investigate the association between maternal GWG (inadequate, adequate, excess) and the risk of offspring obesity.
  • To analyze this association across distinct offspring life stages: early childhood (<5 years), adolescence (5 to <18 years), and adulthood (18+ years).

Main Methods:

  • A systematic review of published literature was conducted.
  • Data were extracted and meta-analyzed to quantify offspring obesity risk relative to maternal GWG.
  • Offspring obesity estimates were stratified by three life stages.

Main Results:

  • Offspring born to mothers with inadequate GWG had a decreased risk of obesity (RR: 0.86, 95% CI: 0.78-0.94).
  • Offspring born to mothers with excess GWG had an increased risk of obesity (RR: 1.40, 95% CI: 1.23-1.59).
  • These associations remained consistent across all analyzed life stages.

Conclusions:

  • Excess gestational weight gain significantly influences offspring obesity risk, both short-term and long-term.
  • Maternal GWG is a critical factor to manage for preventing offspring obesity.
  • Avoiding excess GWG during pregnancy is recommended to mitigate offspring obesity risk.

Keywords:
Body mass indexgestational weight gainobesityoffspring

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