Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Vaccinations01:51

Vaccinations

44.1K
Overview
44.1K
Vaccines01:21

Vaccines

98
Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the...
98
Vaccine Production01:23

Vaccine Production

144
Vaccine production involves a sequence of upstream and downstream processes to generate a safe and effective immunological product. It begins with cultivating microorganisms, such as viruses or bacteria, to obtain antigenic material. For viral vaccines, mammalian host cells are grown in bioreactors and subsequently infected with the target virus. The virus replicates within the host cells, which are lysed to release viral particles. This lysate is then clarified through filtration or...
144
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

1.3K
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
1.3K
Investigation of Disease Outbreaks01:23

Investigation of Disease Outbreaks

74
Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...
74
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

94
Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable...
94

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Committee for Immunization Programme and Registry and changes in the National Immunization Programme in Spain].

Revista espanola de salud publica·2020
Same author

[The cost of vaccination throughout life in Spain].

Revista espanola de salud publica·2020
Same author

Development of a genosensor for peanut allergen ARA h 2 detection and its optimization by surface response methodology.

Biosensors & bioelectronics·2014
Same author

Immunisation against meningococcus B: the case of Spain.

Lancet (London, England)·2014

Related Experiment Video

Updated: May 5, 2026

Particle Agglutination Method for Poliovirus Identification
07:06

Particle Agglutination Method for Poliovirus Identification

Published on: April 20, 2011

15.2K

[Polio vaccines, eradication and posterradication].

Francisco Salmerón García1, Agustín Portela Moreira, Marta Soler Soneira

  • 1División de Productos Biológicos y Biotecnología, Departamento de Medicamentos de Uso Humano, Agencia Española de Medicamentos y Productos Sanitarios (AEMPS), Madrid, España.

Revista Espanola De Salud Publica
|December 11, 2013
PubMed
Summary

Polio eradication relies on herd immunity from oral polio vaccine (OPV) and inactivated polio vaccine (IPV). Phasing out OPV is crucial to prevent vaccine-associated polio cases and achieve global polio elimination.

More Related Videos

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression
10:48

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression

Published on: May 15, 2014

10.9K
Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen
07:44

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen

Published on: May 12, 2023

2.1K

Related Experiment Videos

Last Updated: May 5, 2026

Particle Agglutination Method for Poliovirus Identification
07:06

Particle Agglutination Method for Poliovirus Identification

Published on: April 20, 2011

15.2K
Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression
10:48

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression

Published on: May 15, 2014

10.9K
Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen
07:44

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen

Published on: May 12, 2023

2.1K

Area of Science:

  • Public Health
  • Vaccinology
  • Infectious Disease Control

Background:

  • Herd immunity from oral polio vaccine (OPV) and inactivated polio vaccine (IPV) is key to polio eradication.
  • OPV is cost-effective but can cause vaccine-associated polio cases, unlike the more expensive IPV.
  • The World Health Assembly set a goal in 1988 to interrupt wild poliovirus transmission.

Purpose of the Study:

  • To outline the strategy for global polio eradication and containment of all polioviruses.
  • To detail the necessary steps to prevent paralytic poliomyelitis in children worldwide.
  • To highlight the importance of transitioning away from OPV to achieve eradication.

Main Methods:

  • Implementing a global immunization strategy incorporating IPV.
  • Phasing out specific OPV types, including type 2 OPV and the bivalent oral polio vaccine.
  • Establishing a timeline for the cessation of OPV use and wild poliovirus circulation.

Main Results:

  • The plan aims for no wild polio cases after 2014.
  • Introduction of at least one dose of IPV into all national immunization programs.
  • Cessation of type 2 OPV vaccination by end of 2016 and bivalent OPV in 2019.

Conclusions:

  • Global polio eradication requires a coordinated scientific and economic effort.
  • Transitioning from OPV to IPV is essential to prevent vaccine-associated polio cases.
  • The successful containment of all polioviruses will ensure no child suffers from paralytic poliomyelitis.