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Aggressive pseudomyxoma peritonei: a case report with an unusual clinical presentation

Zisis Touloumis1, George Galyfos, Nikolaos Kavouras

  • 1Department of General Surgery, General Hospital of Chalkis, 48 Gazepi Street, Chalkis, 34100 Evia, Greece.

Case Reports in Oncological Medicine
|December 11, 2013
PubMed

Insights

Pseudomyxoma peritonei (PMP) can present with vague symptoms, complicating diagnosis. Aggressive peritoneal mucinous carcinomatosis (PMCA) may benefit from cytoreductive surgery and chemotherapy despite poor prognosis.

Area of Science:

  • Oncology
  • Surgical Pathology

Background:

  • Pseudomyxoma peritonei (PMP) is a rare clinical condition.
  • Aggressive disease can present atypically.

Purpose of the Study:

  • To report a case of PMP with unusual presentation.
  • To analyze current data on PMP diagnosis and management.

Main Methods:

  • Case report of a 71-year-old male.
  • Diagnostic workup included clinical examination, radiology, tumor markers, and laparotomy with biopsies.
  • Immunohistochemical examination confirmed peritoneal mucinous carcinomatosis (PMCA).

Main Results:

  • Patient presented with non-specific symptoms (diarrhea, loss of appetite) and obesity.
  • Radiology showed ascites and possible appendiceal mucocele.
  • High tumor markers and confirmed aggressive PMCA.

Conclusions:

  • Advanced PMP can have misleading, unspecific symptoms.
  • Cytoreductive surgery and chemotherapy may be considered for aggressive PMCA, even with unfavorable prognosis.

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