Related Experiment Video
Updated: May 5, 2026
09:19
Culture and Imaging of Ex Vivo Organotypic Pseudomyxoma Peritonei Tumor Slices from Resected Human Tumor Specimens
Published on: December 9, 2022
1.9K
Aggressive pseudomyxoma peritonei: a case report with an unusual clinical presentation
Zisis Touloumis1, George Galyfos, Nikolaos Kavouras
1Department of General Surgery, General Hospital of Chalkis, 48 Gazepi Street, Chalkis, 34100 Evia, Greece.
Case Reports in Oncological Medicine
|December 11, 2013
Summary
Pseudomyxoma peritonei (PMP) can present with vague symptoms, complicating diagnosis. Aggressive peritoneal mucinous carcinomatosis (PMCA) may benefit from cytoreductive surgery and chemotherapy despite poor prognosis.
Area of Science:
- Oncology
- Surgical Pathology
Background:
- Pseudomyxoma peritonei (PMP) is a rare clinical condition.
- Aggressive disease can present atypically.
Purpose of the Study:
- To report a case of PMP with unusual presentation.
- To analyze current data on PMP diagnosis and management.
Main Methods:
- Case report of a 71-year-old male.
- Diagnostic workup included clinical examination, radiology, tumor markers, and laparotomy with biopsies.
- Immunohistochemical examination confirmed peritoneal mucinous carcinomatosis (PMCA).
Main Results:
- Patient presented with non-specific symptoms (diarrhea, loss of appetite) and obesity.
- Radiology showed ascites and possible appendiceal mucocele.
- High tumor markers and confirmed aggressive PMCA.
Conclusions:
- Advanced PMP can have misleading, unspecific symptoms.
- Cytoreductive surgery and chemotherapy may be considered for aggressive PMCA, even with unfavorable prognosis.
Related Concept Videos
01:22Appendicitis-I: Introduction
4.4K
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
4.4K
01:19Appendicitis
29
Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
29
01:28Esophageal Perforation-II: Clinical Manifestations and Management
1.1K
Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
Clinical Manifestations:
1.1K