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Updated: May 5, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Psoriasiform drug eruption associated with sodium valproate
Gulen Gul Mert1, Faruk Incecik, Suhan Gunasti
1Division of Pediatric Neurology, Department of Pediatrics, Cukurova University, 01180 Adana, Turkey.
Psoriasis can be triggered by medications. A psoriasiform drug eruption linked to sodium valproate highlights the need for early detection and drug withdrawal for successful treatment.
Area of Science:
- Dermatology
- Pharmacology
Background:
- Psoriasis is a prevalent skin condition.
- Understanding disease triggers is crucial for clinical management.
- Medication use is an increasingly recognized factor influencing psoriasis.
Purpose of the Study:
- To report a case of psoriasiform drug eruption.
- To highlight the association between sodium valproate and this reaction.
- To emphasize physician awareness and early detection.
Main Methods:
- Case report presentation.
- Clinical observation of a patient with a psoriasiform drug eruption.
- Review of medication history, specifically sodium valproate use.
Main Results:
- A patient developed a psoriasiform drug eruption.
- The eruption was associated with the use of sodium valproate.
- Identification and discontinuation of the causative drug are key for treatment.
Conclusions:
- Sodium valproate can induce psoriasiform drug eruptions.
- Physicians must be aware of this potential adverse drug reaction.
- Prompt diagnosis and removal of the offending agent are essential for therapeutic success in managing drug-induced psoriasis.
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