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Updated: May 4, 2026

Kinetic Screening of Nuclease Activity using Nucleic Acid Probes
Published on: November 1, 2019
Synthesis of nitrogen-containing furanose sugar nucleotides for use as enzymatic probes
Ryan B Snitynsky1, Todd L Lowary
1Alberta Glycomics Centre and Department of Chemistry, Gunning-Lemieux Chemistry Centre, University of Alberta , Edmonton, Alberta, Canada T6G 2G2.
Abstract:
The sugar nucleotides UDP-2-acetamido-2-deoxy-α-D-galactofuranose (UDP-GalfNAc) and UDP-2-azido-2-deoxy-α-D-galactofuranose (UDP-GalfN3) have been synthesized in preparative scale for the first time. These compounds are useful probes for studying the biosynthesis of glycans containing galactofuranose and/or 2-acetamido-2-deoxy-α-D-galactofuranose residues.
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