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Related Concept Videos

¹H NMR: Long-Range Coupling01:27

¹H NMR: Long-Range Coupling

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The coupling interactions of nuclei across four or more bonds are usually weak, with J values less than 1 Hz. While these are usually not observed in spectra, the presence of multiple bonds along the coupling pathway can result in observable long-range coupling.
In alkenes, spin information is communicated via σ–π overlap, as seen in allylic (four-bond) and homoallylic (five-bond) couplings. These coupling interactions are stronger when the σ bond is parallel to the alkene...
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Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology
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Long-range connectomics.

Saad Jbabdi1, Timothy E Behrens

  • 1FMRIB Centre, University of Oxford, Oxford, United Kingdom.

Annals of the New York Academy of Sciences
|December 17, 2013
PubMed
Summary
This summary is machine-generated.

Neuroscience aims to decode neural algorithms by understanding brain activity and connectivity. New in vivo tools offer noninvasive methods to measure structural and functional connections, aiding in deciphering the neural code.

Keywords:
brain connectionschemical tracerstractography

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Area of Science:

  • Neuroscience
  • Computational Neuroscience

Background:

  • Decoding neural algorithms is a primary objective in neuroscience.
  • Brain computations depend on coordinated neural activity at local and long-range scales.
  • Understanding the brain activity-connectivity relationship is crucial for deciphering the neural code.

Purpose of the Study:

  • To discuss how recent technological advancements can aid in deciphering the neural code.
  • To highlight the role of new in vivo tools in neuroscience research.

Main Methods:

  • Review of technological advances in connectivity measurement techniques.
  • Focus on new in vivo tools for noninvasive measurement of structural and functional connections.

Main Results:

  • Significant technological progress has been made in measuring brain activity and connectivity.
  • Emerging in vivo tools enable noninvasive assessment of brain connections.

Conclusions:

  • New technologies, particularly in vivo tools, are pivotal for advancing our understanding of neural algorithms.
  • Continued development and application of these tools are essential for cracking the neural code.