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Published on: October 10, 2025
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Navigation-assisted mandibular body distraction osteogenesis: a preliminary study in goats
Ming Cai1, Guofang Shen1, Andrew Hua-an Cheng2
1Department of Oral Craniomaxillofacial Science, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People's Republic of China.
Summary
This study assessed navigation-assisted distraction osteogenesis of the mandible in goats. The TBNavis-CMFS navigation system demonstrated high accuracy in mandibular lengthening, confirming its clinical potential.
Area of Science:
- Oral and Maxillofacial Surgery
- Biomedical Engineering
- Regenerative Medicine
Background:
- Distraction osteogenesis is a surgical technique used to grow bone.
- Accurate bone lengthening is crucial for successful reconstructive surgery.
- Navigation systems can potentially improve the precision of surgical procedures.
Purpose of the Study:
- To evaluate the accuracy of navigation-assisted distraction osteogenesis of the mandible.
- To assess the efficacy of the TBNavis-CMFS navigation system in a preclinical goat model.
Main Methods:
- Six adult goats underwent computed tomography (CT) scans for 3D model reconstruction.
- The TBNavis-CMFS navigation system was used for image-guided mandibular distraction osteogenesis.
- Preoperative simulation was compared with 3-month postoperative 3D skeletal measurements.
Main Results:
- Navigation-assisted distraction osteogenesis was successfully performed in all subjects.
- Intraoperative registration accuracy was within 1 mm.
- Mean mandibular lengthening was 10.02 mm, with no significant difference from planned distraction.
Conclusions:
- The TBNavis-CMFS navigation system enables highly accurate navigation-assisted mandibular distraction osteogenesis.
- This technique shows promise for precise bone regeneration in maxillofacial reconstruction.
