Related Experiment Video
Updated: May 4, 2026
09:11
Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma
Published on: May 24, 2024
1.7K
Outpatient single-session yttrium-90 glass microsphere radioembolization
Vanessa L Gates1, Karen G Marshall2, Krystina Salzig2
1Department of Radiology, Section of Nuclear Medicine, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, 676 North St Clair, Suite 800, Chicago, IL 60611.
Journal of Vascular and Interventional Radiology : JVIR
|December 17, 2013
Summary
This study demonstrates that yttrium-90 (90Y) glass microsphere radioembolization can be safely performed as a single-session, outpatient procedure. This approach streamlines patient care and reduces overall treatment costs.
Area of Science:
- Interventional Radiology
- Nuclear Medicine
- Oncology
Background:
- Radioembolization is a common treatment for liver tumors.
- Current protocols often involve multiple sessions, increasing patient burden and costs.
Purpose of the Study:
- To assess the feasibility of yttrium-90 (90Y) glass microsphere radioembolization as a single-session, outpatient procedure.
- To evaluate the safety and efficiency of this streamlined approach.
Main Methods:
- 14 patients underwent single-session, outpatient radioembolization with 90Y glass microspheres.
- Procedures included diagnostic imaging (CT/MRI), planning angiography with cone-beam CT, technetium-99m macroaggregated albumin ((99m)Tc-MAA) administration for lung shunt assessment, and 90Y delivery.
- Dosimetry calculations were completed on the treatment day.
Main Results:
- All 14 patients successfully completed the single-session outpatient procedure without complications.
- The mean total procedure time was 2.70 hours.
- Treatments were delivered to the intended dose in all cases.
Conclusions:
- Single-session, outpatient radioembolization with 90Y glass microspheres is feasible.
- This approach reduces the time from initial assessment to treatment.
- The method offers potential cost savings and improved patient convenience.
