Standardization of Tc-99 by three liquid scintillation counting methods
W M van Wyngaardt1, M J van Staden1, J Lubbe1
1National Metrology Institute of South Africa, 15 Lower Hope Road, Rosebank, 7700 Cape Town, South Africa.
Summary
The National Metrology Institute of South Africa validated Technetium-99 (Tc-99) radioactivity measurements using three methods. Results confirmed the accuracy of the latest (2011) decay data evaluation for Tc-99.
Area of Science:
- Metrology
- Nuclear Science
- Radiochemistry
Background:
- International key comparisons are crucial for harmonizing radioactivity measurements globally.
- Accurate standardization of pure beta emitters like Technetium-99 (Tc-99) is essential for various applications.
Purpose of the Study:
- To participate in the international key comparison CCRI(II)-K2.Tc-99 for Tc-99.
- To validate the standardization of Tc-99 solutions using multiple independent methods.
Main Methods:
- Utilized three distinct methods for radioactivity standardization: TDCR efficiency calculation, CIEMAT/NIST efficiency tracing, and 4π(LS)β-γ coincidence tracing.
- Employed Cobalt-60 (Co-60) as a tracer in the coincidence method.
- Compared results against the latest (2011) Decay Data Evaluation Project (DDEP) evaluation of Tc-99 decay data.
Main Results:
- Achieved excellent agreement between the results obtained from the three independent standardization methods.
- Demonstrated consistency in radioactivity measurements for Tc-99.
Conclusions:
- The study confirms the reliability of the three applied methods for Tc-99 standardization.
- Validated the applicability of the 2011 DDEP evaluation for Tc-99 beta spectral shape, superseding the 2004 evaluation.
Related Concept Videos
01:25Imaging Studies II: Positron Emission Tomography and Scintigraphy
853
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Fundamental Principles of PET
853
01:21Atomic Absorption Spectroscopy: Lab
1.3K
For AAS measurements, samples must be introduced as clear solutions, often requiring extensive preliminary treatment to dissolve materials like soils, animal tissues, and minerals. Common methods for sample preparation include treatment with hot mineral acids, wet ashing, combustion in closed containers, high-temperature ashing, or fusion with reagents.
Solutions containing organic solvents, such as low-molecular-mass alcohols, esters, or ketones, enhance absorbances by increasing...
Solutions containing organic solvents, such as low-molecular-mass alcohols, esters, or ketones, enhance absorbances by increasing...
1.3K
01:11Glassware Calibration
2.0K
Accurate calibration of glassware, such as volumetric flasks, pipettes, and burettes, is essential to ensure accurate measurements in the analytical laboratory. Calibration helps maintain consistency across measurements and prevents errors arising from inaccurate volumes.
Volumetric flasks: Volumetric flasks are designed to prepare aqueous solutions of precise volumes accurately with a calibration line on the neck. To calibrate a volumetric flask, it is important to fill it with distilled...
Volumetric flasks: Volumetric flasks are designed to prepare aqueous solutions of precise volumes accurately with a calibration line on the neck. To calibrate a volumetric flask, it is important to fill it with distilled...
2.0K
01:08Titrimetric Methods: Types and Commonly Used Strategies
2.2K
In chemistry, titrimetric methods are broadly classified into three types: volumetric, gravimetric, and coulometric. Volumetric titrations involve measuring the volume of a titrant of known concentration that is required to react completely with an analyte. In gravimetric titrations, the standard solution reacts with the analyte to form an insoluble precipitate, which is filtered, dried, and weighed. In coulometric titrations, current is applied to an electrochemical reaction until the reaction...
2.2K