Related Experiment Video
Updated: May 4, 2026

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
Published on: January 25, 2016
[Corticotherapy withdrawal in older people]
Frédérique Retornaz1, Sandrine Boullu-Ciocca2, Anaïs Farcet3
1Pôle gériatrique, Centre gérontologique départemental, Marseille, France, EA3279, Évaluation des systèmes de soins - Santé perçue, Faculté de médecine, Aix Marseille Université, Marseille, France.
Abstract:
Synthetic glucocorticoids treatment for their antiinflammatory and immunosuppressive activities for more than 3 weeks decreases corticotropic axis and induces a risk of adrenal insufficiency upon treatment withdrawal. Dose, duration and unknown individual factors play a role in the occurrence of adrenal insufficiency. Serum cortisol at 7-8 am, possibly completed by an 1-24 ACTH stimulation test makes the diagnosis. A scheme for care of patients is included with a progressive decrease of synthetic glucocorticoids dose, a replacement of this medication with physiological doses of hydrocortisone (in case of adrenal insufficiency) and a follow-up of endogenous secretion for detection of adrenal function recovery.
More Related Videos
04:59Heat-sensitive Moxibustion as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Insomnia
Published on: May 30, 2025
06:52Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit
Published on: September 30, 2020
Related Concept Videos
Pharmacodynamics in Geriatric Patients: Effects of Age
Drug Dosing: Geriatric Patients
COPD: Management Using Bronchodilators and Corticosteroids
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion
Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption