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Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

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[Neurosyphilis and cognitive disorders].

Anne Forest¹, Zina Barrou¹, Marc Verny¹

¹Service de gériatrie, Hôpital Pitié Salpêtrière, Paris, France.

Geriatrie Et Psychologie Neuropsychiatrie Du Vieillissement

|December 17, 2013

Summary

This summary is machine-generated.

A severe delirium in a 75-year-old man was linked to neurosyphilis and early Alzheimer's disease. This case highlights the complex interplay of infections and neurodegenerative conditions in elderly cognitive impairment.

Keywords:

delirium dementia multiple pathologies neurodegenerative diseases neurosyphilis

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Area of Science:

Neurology
Infectious Diseases
Geriatrics

Background:

Delirium presents diagnostic challenges in the elderly.
Neurosyphilis and Alzheimer's disease are significant causes of cognitive decline.

Observation:

A 75-year-old male presented with severe and prolonged delirium.
Underlying conditions included neurosyphilis (an infectious disease) and prodromal Alzheimer's disease.

Findings:

The co-occurrence of neurosyphilis and Alzheimer's disease likely contributed to the delirium's severity.
Cerebral neurosyphilis diagnosis is complex, with varied cognitive and behavioral symptoms.

Implications:

This case underscores the cumulative impact of multimorbidity on elderly patients' clinical presentations.
Recognizing concurrent causes of cognitive impairment is crucial for accurate diagnosis and management in geriatric care.