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Related Experiment Video

Updated: May 4, 2026

Generation of Alginate Microspheres for Biomedical Applications

Generation of Alginate Microspheres for Biomedical Applications

Published on: August 12, 2012

Injectable alginate hydrogels for cell delivery in tissue engineering.

Sílvia J Bidarra¹, Cristina C Barrias¹, Pedro L Granja²

¹INEB - Instituto de Engenharia Biomédica, Universidade do Porto, Rua do Campo Alegre, 823, 4150-180 Porto, Portugal.

Acta Biomaterialia

|December 17, 2013

Summary

Injectable alginate hydrogels show great promise for tissue regeneration by delivering cells effectively. These adaptable biomaterials offer minimally invasive delivery and contourability for various biomedical applications.

Keywords:

Alginate Cell delivery Injectable Regeneration Tissue engineering

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Last Updated: May 4, 2026

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Synthesis of Thermogelling PolyN-isopropylacrylamide-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering

Synthesis of Thermogelling PolyN-isopropylacrylamide-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering

Published on: October 26, 2016

Area of Science:

Biomaterials Science
Regenerative Medicine
Tissue Engineering

Background:

Alginate hydrogels are versatile biomaterials with extracellular matrix-like properties, making them suitable for cell delivery in tissue regeneration.
Recent advancements allow for biofunctionalization and property modulation, enhancing their adaptability for specific applications.
Injectable formulations offer advantages like mild therapeutic agent incorporation, minimally invasive delivery, and defect contourability.

Purpose of the Study:

To review the in vitro and in vivo potential of injectable alginate hydrogels for targeted cell delivery.
To highlight key aspects of studies using alginate hydrogels for cell delivery, including crosslinking methods, cell types, and target tissues.

Main Methods:

Literature review of studies investigating injectable alginate hydrogels for cell delivery.
Analysis of crosslinking strategies, cell types employed, and target tissues for regeneration.
Evaluation of in vitro and in vivo outcomes reported in the selected studies.

Main Results:

Alginate hydrogels have been successfully employed as cell delivery vehicles across various tissues and organs.
The choice of crosslinking method and cell type influences the efficacy of tissue regeneration.
Injectable alginate hydrogels demonstrate potential for targeted cell delivery and enhanced regeneration.

Conclusions:

Injectable alginate hydrogels are promising for cell-based therapies in tissue regeneration.
Tailoring alginate hydrogel properties and delivery strategies is crucial for optimizing therapeutic outcomes.
Further research into alginate hydrogel systems can advance cell delivery for diverse biomedical applications.