Related Experiment Video

Updated: Aug 11, 2026

Quantifying Agonist Activity at G Protein-coupled Receptors
11:45

Quantifying Agonist Activity at G Protein-coupled Receptors

Published on: December 26, 2011

[pGlu6,Pro9]SP6-11, a selective agonist for the substance P P-receptor subtype

R Laufer, C Gilon, M Chorev

    Journal of Medicinal Chemistry
    |July 1, 1986
    PubMed
    Summary

    A single amino acid change in substance P analogue [pGlu6]SP6-11 creates [pGlu6,Pro9]SP6-11, a selective SP-P receptor agonist. This peptide distinguishes between muscular and neuronal tachykinin receptors, enabling specific bioassays.

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