Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sexually Transmitted Infections01:26

Sexually Transmitted Infections

2.0K
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
2.0K
Viral Hepatitis I: Introduction01:28

Viral Hepatitis I: Introduction

25
Viral hepatitis is an inflammatory condition of the liver caused by infection with hepatotropic viruses, most commonly hepatitis A, B, C, D, and E. Despite variations in structure and transmission, all viruses mentioned infect hepatocytes and provoke immune responses that can hinder liver function. Additionally, some non-hepatotropic viruses can also lead to hepatic inflammation.Hepatitis A VirusHepatitis A virus (HAV) is transmitted through the fecal–oral route, typically by ingestion...
25
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

102
Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
102
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

94
Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable...
94
Infection01:20

Infection

11.6K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
11.6K
Retroviruses02:33

Retroviruses

12.1K
Retroviruses and retrotransposons both insert copies of their genetic elements into the genome of the host cell. Thus, the viral genes are passed on when the host genome is replicated or translated. A typical retroviral DNA sequence contains 3-4 genes that encode the different proteins required for its structural assembly and function as a molecular parasite. This DNA is transcribed into a single mRNA, which is very similar in structure to conventional mRNAs, i.e., it is capped at the 5’...
12.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pediatric inpatient influenza vaccination before, during and after the COVID-19 pandemic.

Journal of the Pediatric Infectious Diseases Society·2026
Same author

Rotavirus Vaccine Coverage and Potential Barriers Among US Children Born From 2007 to 2024.

Pediatrics·2026
Same author

COVID-19 and Influenza Vaccine Acceptance and Hesitancy Among Caregivers of Children With Cancer.

Journal of pediatric hematology/oncology·2026
Same author

Influenza Vaccine Communication During Pediatric Hospitalizations: A Qualitative Study.

Hospital pediatrics·2026
Same author

Correction: The Children's Hospitals in Africa Mapping Project (CHAMP) survey: Facilities, equipment, supplies, infrastructure, and capacity to respond to emergencies.

PLOS global public health·2026
Same author

Factors associated with perceived weight gain among the adult population of Kazakhstan during the COVID-19 pandemic.

PloS one·2025

Related Experiment Video

Updated: May 4, 2026

Isolation of Lymphocytes from Mouse Genital Tract Mucosa
04:46

Isolation of Lymphocytes from Mouse Genital Tract Mucosa

Published on: September 3, 2012

14.1K

Current thinking on genital herpes.

Annika M Hofstetter1, Susan L Rosenthal, Lawrence R Stanberry

  • 1Department of Pediatrics, Columbia University; NewYork-Presbyterian Hospital, New York, New York, USA.

Current Opinion in Infectious Diseases
|December 17, 2013
PubMed
Summary
This summary is machine-generated.

Genital herpes simplex virus (HSV) infections are common globally. Recent research shows HSV-1 is increasingly prevalent, and asymptomatic shedding contributes to high transmission rates, necessitating new prevention strategies.

More Related Videos

Porcine Corneal Tissue Explant to Study the Efficacy of Herpes Simplex Virus-1 Antivirals
08:31

Porcine Corneal Tissue Explant to Study the Efficacy of Herpes Simplex Virus-1 Antivirals

Published on: September 20, 2021

2.7K
A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation
12:22

A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation

Published on: April 2, 2012

17.2K

Related Experiment Videos

Last Updated: May 4, 2026

Isolation of Lymphocytes from Mouse Genital Tract Mucosa
04:46

Isolation of Lymphocytes from Mouse Genital Tract Mucosa

Published on: September 3, 2012

14.1K
Porcine Corneal Tissue Explant to Study the Efficacy of Herpes Simplex Virus-1 Antivirals
08:31

Porcine Corneal Tissue Explant to Study the Efficacy of Herpes Simplex Virus-1 Antivirals

Published on: September 20, 2021

2.7K
A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation
12:22

A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation

Published on: April 2, 2012

17.2K

Area of Science:

  • Infectious Diseases
  • Immunology
  • Epidemiology

Background:

  • Genital herpes, caused by herpes simplex virus (HSV), presents a significant global health challenge.
  • Understanding recent advancements in HSV infections is crucial for public health.

Purpose of the Study:

  • To review recent advances in the understanding of genital herpes simplex virus (HSV) infections.
  • To highlight changes in epidemiology, pathogenesis, and host immunity related to genital herpes.

Main Methods:

  • Literature review of recent studies on genital herpes simplex virus (HSV).
  • Analysis of epidemiological data, immune responses, and therapeutic developments.

Main Results:

  • Increasing proportion of genital herpes cases linked to HSV type 1.
  • Frequent, asymptomatic shedding episodes contribute to high HSV transmission.
  • Host immune responses, particularly T cell activity, are critical for controlling HSV.
  • Novel prophylactic and therapeutic strategies are under development.

Conclusions:

  • Improved knowledge of HSV epidemiology, pathogenesis, and immunity can inform new prevention and control strategies.
  • Despite advances, much remains unknown about genital herpes, underscoring the need for continued research.