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Somatomedin C deficiency in Asian sisters

M E McGraw, D A Price, D J Hill

Archives of Disease in Childhood

|December 1, 1986

Abstract:

Two sisters of Asian origin showed typical clinical and biochemical features of primary somatomedin C (SM-C) deficiency (Laron dwarfism). Abnormalities of SM-C binding proteins were observed, one sister lacking the high molecular weight (150 Kd) protein.

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