Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Microbial Biosensors

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Stacking of MoS<sub>2</sub> monolayers by sequential electrochemical thinning of bulk crystals.

Chemical communications (Cambridge, England)·2026

Same author

Stretchable Laser-Induced Graphene Electrodes for High-Performance Electrochemical Biosensing of Lactate in Sweat.

ACS sensors·2026

Same author

Switchable Electrode-Enabled High-Density Two-Dimensional Chips: A Simple, Generalizable Approach to Yield High-Throughput Electrochemical Analyses.

ACS sensors·2026

Same author

Hollow polydopamine spheres decorated with MoS<sub>2</sub> nanosheets for the hydrogen evolution reaction.

Chemical communications (Cambridge, England)·2026

Same author

Tuning the Chemical and Electrochemical Properties of Paper-Based Carbon Electrodes by Pyrolysis of Polydopamine.

ACS measurement science au·2024

Same author

Ultradense Electrochemical Chips with Arrays of Nanostructured Microelectrodes to Enable Sensitive Diffusion-Limited Bioassays.

ACS applied materials & interfaces·2024

Search research articles

Related Experiment Video

Updated: May 4, 2026

Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays

Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays

Published on: March 9, 2017

Microfluidic paper-based devices for bioanalytical applications.

Murilo Santhiago¹, Emilia W Nery, Glauco P Santos

¹Department of Analytical Chemistry, Institute of Chemistry - UNICAMP, P.O.Box 6154, 13084-971, Campinas, SP, Brazil.

|December 18, 2013

Summary

This summary is machine-generated.

Paper-based microfluidic devices offer versatile applications in health diagnostics and environmental monitoring. This review covers fabrication techniques, detection methods, recent bioanalysis advancements, and future trends for these analytical systems.

More Related Videos

Author Spotlight: Revolutionizing Microfluidics Through Microchannel Fabrication on Nanopaper

Author Spotlight: Revolutionizing Microfluidics Through Microchannel Fabrication on Nanopaper

Published on: October 6, 2023

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

Related Experiment Videos

Last Updated: May 4, 2026

Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays

Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays

Published on: March 9, 2017

Author Spotlight: Revolutionizing Microfluidics Through Microchannel Fabrication on Nanopaper

Author Spotlight: Revolutionizing Microfluidics Through Microchannel Fabrication on Nanopaper

Published on: October 6, 2023

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

Area of Science:

Analytical Chemistry
Materials Science
Biotechnology

Background:

Paper is a cost-effective and accessible substrate for microfluidic device fabrication.
Paper-based analytical devices (PADs) have emerged as promising tools for various applications.
These devices offer advantages like portability, ease of use, and minimal sample/reagent consumption.

Purpose of the Study:

To provide a historical overview of paper-based analytical systems.
To summarize fabrication techniques, their pros and cons.
To review novel bioanalytical achievements and future trends in paper microfluidics.

Main Methods:

Literature review focusing on paper microfluidics and bioanalysis.
Analysis of fabrication methods for paper-based devices.
Exploration of diverse detection techniques including colorimetric, electrochemical, and chemiluminescence methods.

Main Results:

Paper microfluidics presents a growing field with diverse fabrication and detection strategies.
Recent advancements highlight novel bioanalytical applications and improved device performance.
Key detection methods include colorimetric, electrochemical, photoelectrochemical, chemiluminescence, and electrochemiluminescence.

Conclusions:

Paper-based microfluidic devices are rapidly evolving for point-of-care diagnostics and environmental sensing.
Continued innovation in fabrication and detection methods will expand their utility.
Future trends point towards integrated, multiplexed, and highly sensitive paper analytical systems.