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Endoscopic diagnosis in a Tunisian pediatric population with upper gastrointestinal bleeding

Sonia Mazigh Mrad, Samir Boukthir, Ines Brini

    La Tunisie Medicale
    |December 18, 2013
    PubMed

    Insights

    Upper gastrointestinal bleeding (UGIB) causes in children vary by age. Peptic esophagitis and gastritis were more common in infants than older children, indicating age-related differences in UGIB etiology.

    Area of Science:

    • Pediatric Gastroenterology
    • Endoscopy
    • Gastrointestinal Bleeding

    Background:

    • Esophagogastroduodenoscopy (EGD) is the standard diagnostic procedure for Upper Gastrointestinal Bleeding (UGIB).
    • Limited studies exist on UGIB causes in children within certain regions.

    Purpose of the Study:

    • To identify common causes of UGIB in pediatric patients.
    • To determine if UGIB causes differ based on age groups in developing and developed countries.

    Main Methods:

    • Retrospective review of medical records for children undergoing EGD for UGIB.
    • Categorization of patients into neonates, infants, and children/adolescents.
    • Analysis of etiological factors and endoscopic findings.

    Main Results:

    • 614 EGDs were analyzed; etiology remained undetermined in 20.68% of cases.
    • Mucosal lesions were common in neonates; toxic drug intake was noted in 140 patients.
    • Peptic esophagitis and gastritis were significantly more prevalent in infants compared to older children (p=0.015 and p≤0.001, respectively).
    • Peptic ulcers, Mallory Weiss tears, and variceal lesions were also identified.

    Conclusions:

    • The etiologies of UGIB in children in Tunisia are diverse and age-dependent.
    • Findings highlight the need for age-specific diagnostic and treatment approaches for pediatric UGIB.
    Abstract

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