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Published on: January 28, 2019
African rotavirus surveillance network: a brief overview
Jason M Mwenda1, Jacqueline E Tate, Umesh D Parashar
1From the *World Health Organization, Regional Office for Africa, Brazzaville, Republic of Congo; †National Center for Immunization and Respiratory Diseases, CDC, Atlanta, GA; and ‡World Health Organization, Geneva, Switzerland.
Insights
Reliable rotavirus disease burden data is crucial for African countries to inform decisions on introducing new rotavirus vaccines. Sentinel surveillance platforms are generating country-specific evidence for policy-making in diarrhea control.
Area of Science:
- Public Health
- Infectious Diseases
- Vaccinology
Background:
- Rotavirus gastroenteritis is a major cause of childhood diarrhea globally.
- New rotavirus vaccines are becoming available, necessitating data on disease burden for informed introduction.
- Effective diarrhea control strategies require accurate, country-specific epidemiological data.
Purpose of the Study:
- To establish and utilize sentinel surveillance systems across African nations.
- To generate reliable data on the burden of rotavirus diarrhea in children under 5 years.
- To support evidence-based decision-making for rotavirus vaccine introduction and national immunization programs.
Main Methods:
- Implementing standardized guidelines for rotavirus diarrhea surveillance.
- Focusing surveillance on children under 5 years of age.
- Utilizing World Health Organization supported platforms since 2006.
Main Results:
- African countries are generating high-quality, country-specific data on rotavirus gastroenteritis burden.
- Surveillance data provides evidence for the impact of rotavirus disease.
- The generated data is actively used by policymakers.
Conclusions:
- Sentinel surveillance is effective in documenting rotavirus disease burden in Africa.
- Data generated informs policy decisions on rotavirus vaccine introduction.
- This evidence supports the integration of rotavirus vaccines into national immunization programs for diarrhea control.
Abstract:
With the imminent availability of new and prospective rotavirus vaccines, reliable information on burden of rotavirus diseases in the different African countries was required to enable evidence-based decision making regarding introduction of rotavirus vaccines. World Health Organization has been supporting Member States since 2006 to establish sentinel surveillance for rotavirus diarrhea in children <5 years of age using standardized guidelines. African countries are using this platform to generate high quality country specific data to document and demonstrate the burden of rotavirus gastroenteritis. The data gathered are being used by policy makers to guide decisions on appropriate intervention strategies for diarrhea control including the value and timing of the introduction of new rotavirus vaccines in the national immunization programs.
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