Related Experiment Video
Updated: May 4, 2026
09:06
MicroRNA Amplification and Recognition through Locked-nucleic-acid In situ Hybridization as a Novel Detection and Quantification Method
Published on: October 7, 2025
555
Colorimetric detection of microRNA miR-21 based on nanoplasmonic core-satellite assembly
1School of Integrated Technology, Yonsei Institute of Convergence Technology, Yonsei University, Incheon, 406-840, Korea. jongsoukyeo@yonsei.ac.kr.
Chemical Communications (Cambridge, England)
|December 19, 2013
Abstract:
In order to detect microRNAs (miRNAs), we developed a colorimetric sensing method on the basis of the plasmonic coupling effect. Gold nanoplasmonic particles (GNPs) are assembled in a core-satellite configuration in the presence of target miRNA, inducing remarkable changes in the scattering color and spectra at the picomolar level with selectivity.
Related Concept Videos
01:22MicroRNAs
21.1K
MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After...
21.1K
01:22MicroRNAs
3.0K
MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between genes). Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself, forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA...
3.0K
01:22MicroRNAs
9.8K
9.8K