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Lymphocytoma cutis--case report.
Ederson Valei Lopes de Oliveira, Giovana Bachega Badiale1, Margarida M F S Moraes2
1University of de São Paulo, Medical School, Ribeirão PretoSP, Brazil.
Anais Brasileiros De Dermatologia
|December 19, 2013
Summary
This case study details lymphocytoma cutis treatment in a 62-year-old male. Intralesional triamcinolone injections after partial response to PUVA phototherapy led to significant lesion regression.
Area of Science:
- Dermatology
- Oncology
- Immunohistochemistry
Background:
- Lymphocytoma cutis, also known as Spiegler-Fendt sarcoid, is a rare benign lymphoid proliferation of the skin.
- Diagnosis often requires a combination of clinical presentation, histopathology, and immunohistochemistry.
Observation:
- A 62-year-old male presented with lymphocytoma cutis in the cephalic region.
- Initial treatment involved 13 PUVA phototherapy sessions, resulting in partial improvement.
- Subsequent intralesional triamcinolone injections were administered every three weeks.
Findings:
- Pathological study and immunohistochemistry confirmed lymphocytoma cutis, showing evidence of polyclonality.
- Five sessions of intralesional triamcinolone resulted in satisfactory improvement, with regression of nearly all lesions.
Implications:
- This case highlights the potential efficacy of intralesional triamcinolone as a treatment for lymphocytoma cutis, particularly after suboptimal response to phototherapy.
- Further research may explore optimal treatment strategies for this rare condition.