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Related Experiment Video

Updated: May 4, 2026

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

Published on: June 13, 2018

Cutaneous protothecosis--case report.

Pâmela Craveiro Gomes da Silva¹, Sabrina Beirão da Costa e Silva¹, Ricardo Barbosa Lima¹

¹Federal University of the State of Rio de Janeiro, Gaffree & Guinle University Hospital, Dermatology Section, Rio de JaneiroRJ, Brazil.

Anais Brasileiros De Dermatologia

|December 19, 2013

Summary

Cutaneous protothecosis, a rare algal skin infection, presents as non-specific lesions. Diagnosis relies on identifying Prototheca algae via histopathology and culture, crucial for effective treatment.

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Area of Science:

Dermatology
Infectious Diseases
Mycology

Background:

Cutaneous protothecosis is a rare infection caused by achlorophyllic algae of the genus Prototheca.
Lesions typically appear on exposed areas, often associated with trauma, particularly in immunocompromised individuals.

Observation:

The clinical presentation is often non-specific, mimicking bacterial, fungal, or herpetic infections, or eczema.
Commonly observed are vesicobullous and ulcerative lesions with pustules and scabs.

Findings:

Diagnosis is confirmed by identifying the Prototheca species through histopathology, culture, and carbohydrate assimilation tests.
Characteristic findings include morula-like spherules, indicative of Prototheca.

Implications:

The rarity and non-specific clinical features of cutaneous protothecosis can delay diagnosis.
Prompt and accurate diagnosis is essential for appropriate management and to prevent disease progression.