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Atypical B12 deficiency with nonresolving paraesthesia
S Haider1, N Ahmad1, E J Anaissie2
1Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.
Abstract:
Vitamin B12 deficiency can present with various hematological, gastrointestinal and neurological manifestations. We report a case of elderly female who presented with neuropathy and vitamin B12 deficiency where the final work-up revealed polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS). This case suggests that, although POEMS syndrome is a rare entity, it can present with vitamin-B12 deficiency and thus specific work up for early diagnosis of POEMS should be considered in patients with B12 deficiency unresponsive to therapy.
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