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Updated: May 4, 2026

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A High Throughput Screen for Biomining Cellulase Activity from Metagenomic Libraries
Published on: February 1, 2011
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Creation of artificial cellulosomes on DNA scaffolds by zinc finger protein-guided assembly for efficient cellulose
Qing Sun1, Bhawna Madan, Shen-Long Tsai
1Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware 19716, USA. wilfred@udel.edu.
Abstract:
For the first time, artificial cellulosome structures were created on DNA scaffolds based on zinc finger protein (ZFP)-guided assembly. These resulting two-component cellulosome structures exhibited enhancement in cellulose hydrolysis compared to the non-complexed mixture depending on the number of CBMs and cellulases assembled.

