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Cancer Therapies02:49

Cancer Therapies

8.5K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
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Cancer Therapies02:49

Cancer Therapies

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Treatment Resistant Cancers02:56

Treatment Resistant Cancers

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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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Cancer Prevention02:59

Cancer Prevention

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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
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Cancer Prevention02:59

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Related Experiment Video

Updated: May 4, 2026

Genome-Wide CRISPR Screen for Unveiling Radiosensitive and Radioresistant Genes
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Rethinking the war on cancer.

Douglas Hanahan1

  • 1Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences. Swiss Federal Institute of Technology Lausanne (EPFL), CH-1015 Lausanne, Switzerland.

Lancet (London, England)
|December 20, 2013
PubMed
Summary

The war on cancer requires a new strategy beyond the "war" and "magic bullet" metaphors. Embracing a "battlespace vision" is crucial for overcoming cancer

Area of Science:

  • Oncology
  • Cancer Research
  • Medical Metaphors

Background:

  • The
  • The

Purpose of the Study:

  • To propose a new strategic framework for cancer research and treatment, moving beyond outdated metaphors.

Main Methods:

  • Conceptual analysis of historical and current approaches to cancer treatment.

Main Results:

  • Current cancer strategies, inspired by 'war' and 'magic bullets,' have limitations due to cancer's adaptive resistance.

Conclusions:

  • A 'battlespace vision,' akin to modern warfare, is necessary to effectively combat cancer and overcome treatment resistance.

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