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Updated: May 4, 2026
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Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct
Published on: April 1, 2022
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Acute pancreatitis during pregnancy: a review
Summary
Pregnancy and acute pancreatitis (AP) is a severe condition. Early diagnosis and multidisciplinary care improve maternal-fetal outcomes, with management tailored to etiology and gestational age.
Area of Science:
- Obstetrics and Gynecology
- Gastroenterology
- Critical Care Medicine
Background:
- Acute pancreatitis (AP) during pregnancy is rare but severe, carrying high maternal-fetal mortality.
- Incidence peaks in the third trimester or early postpartum.
- Common causes include gallstones, alcohol abuse, and hypertriglyceridemia.
Purpose of the Study:
- To review current understanding of AP in pregnancy.
- Emphasize pregnancy complications, birth outcomes, and etiology-specific management.
- Highlight the importance of a multidisciplinary approach.
Main Methods:
- Review of recent literature on AP in pregnancy.
- Application of established AP severity criteria (Ranson, Balthazar) in pregnant patients.
- Discussion of management strategies based on gestational age and etiology.
Main Results:
- Maternal-fetal mortality has decreased due to improved diagnosis and intensive care.
- Fetal risks include preterm labor, prematurity, and intrauterine fetal death.
- High recurrence risk (70%) with conservative treatment for gallstone pancreatitis.
Conclusions:
- Management of AP during pregnancy requires a tailored, multidisciplinary approach.
- Treatment strategies vary by trimester, including conservative measures, cholecystectomy, and ERCP.
- Collaboration between gastroenterologists and obstetricians is crucial for optimal outcomes.
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