Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Local Anesthetics: Differential Sensitivity of Nerve Fibers01:24

Local Anesthetics: Differential Sensitivity of Nerve Fibers

1.8K
Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
1.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Longevity of Amalgam Versus Composite Resin Restorations in Permanent Posterior Teeth: A Systematic Review.

Cureus·2025
Same author

Comparison of Revascularization and Apexification Using Mineral Trioxide Aggregate in Young Human Immature Nonvital Teeth: A Systematic Review and Meta-Analysis.

Cureus·2025
Same author

Endodontic retreatment practice trends among dental surgeons: A survey-based research.

Journal of conservative dentistry and endodontics·2024
Same author

Developing a User-Centered Digital Clinical Decision Support App for Evidence-Based Medication Recommendations for Type 2 Diabetes Mellitus: Prototype User Testing and Validation Study.

JMIR human factors·2021
Same author

Resection of Unresectable Stage IVB Thyroid Cancer Encasing the Carotid Artery.

The Indian journal of surgery·2016
Same author

Designing and evaluating a health belief model-based intervention to increase intent of HPV vaccination among college males.

International quarterly of community health education·2013

Related Experiment Video

Updated: May 4, 2026

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
07:07

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice

Published on: January 12, 2017

10.8K

An insight into dentin desensitizing agents--in vivo study.

Purvi Mehta1, N Vimala, Lalitagauri Mandke

  • 1Dr. Dnyandeo Yashwantrao Patil Dental College and Hospital, Nerul, Navi Mumbai, Maharashtra, India.

Indian Journal of Dental Research : Official Publication of Indian Society for Dental Research
|December 21, 2013
PubMed
Summary

Four agents effectively treated dentin hypersensitivity. Natural resin (propolis) showed the best clinical response, followed by sodium fluoride, offering relief from this common dental condition.

More Related Videos

Inducing Apical Periodontitis in Mice
10:26

Inducing Apical Periodontitis in Mice

Published on: August 6, 2019

12.3K
Author Spotlight: Establishing an Accurate Microhardness Testing Protocol for Craniofacial Tissues
06:16

Author Spotlight: Establishing an Accurate Microhardness Testing Protocol for Craniofacial Tissues

Published on: April 26, 2024

1.5K

Related Experiment Videos

Last Updated: May 4, 2026

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
07:07

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice

Published on: January 12, 2017

10.8K
Inducing Apical Periodontitis in Mice
10:26

Inducing Apical Periodontitis in Mice

Published on: August 6, 2019

12.3K
Author Spotlight: Establishing an Accurate Microhardness Testing Protocol for Craniofacial Tissues
06:16

Author Spotlight: Establishing an Accurate Microhardness Testing Protocol for Craniofacial Tissues

Published on: April 26, 2024

1.5K

Area of Science:

  • Dentistry
  • Dental Materials Science

Background:

  • Dentin hypersensitivity significantly impacts patient quality of life and oral function.
  • Effective management of dentin hypersensitivity is crucial for patient comfort and well-being.

Purpose of the Study:

  • To compare the efficacy of four different desensitizing agents for treating dentin hypersensitivity.
  • To evaluate agents containing hydroxyapatite, potassium nitrate, sodium fluoride, and natural resin (propolis).

Main Methods:

  • An in vivo study involving 40 patients.
  • Baseline pain perception recorded using the Visual Analog Scale (VAS).
  • Comparison of desensitizing agents based on VAS score changes after 7 days, analyzed using Kruskal-Wallis and Mann-Whitney tests.

Main Results:

  • All four tested desensitizing agents demonstrated effectiveness in relieving dentin hypersensitivity.
  • No statistically significant differences in efficacy were observed among the agents.
  • Propolis (natural resin-containing agent) exhibited the most favorable clinical response, followed by the sodium fluoride-containing agent.

Conclusions:

  • Propolis emerges as a safe, natural, and effective option for managing dentin hypersensitivity.
  • Sodium fluoride also presents a viable alternative for desensitization treatment.
  • Further research may explore optimal formulations and long-term efficacy of natural agents.