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Updated: May 4, 2026

Rat Model of Photochemically-Induced Posterior Ischemic Optic Neuropathy
Published on: November 29, 2015
Spontaneous superior ophthalmic vein thrombosis: a rare entity with potentially devastating consequences
L H Lim1, R L Scawn2, K M Whipple2
11] Division of Oculofacial Plastic and Reconstructive Surgery, UCSD Shiley Eye Center, La Jolla, CA, USA [2] Oculoplastic Service, Singapore National Eye Center, Singapore, Singapore.
Purpose:
Spontaneous superior ophthalmic vein thrombosis (SOVT) is a rare entity. We describe three patients with spontaneous ophthalmic vein thrombosis, each with various risk factors.
Patients And Methods:
A retrospective review of three patients with a diagnosis of superior ophthalmic vein thrombosis. Clinical characteristics, radiographic features, management techniques and outcomes are described.
Results:
All patients presented with unilateral painful proptosis. Two patients had intact light perception, whereas one patient presented with absent light perception. All patients had identifiable risk factors for thrombosis, which included sickle cell trait, hereditary hemorrhagic telangectasia and colon cancer with recurrent deep vein thrombosis. Anticoagulation was initiated in two patients. Resolution of proptosis was seen in all patients, with no recovery of vision in one patient.
Conclusions:
Risk factors for spontaneous superior ophthalmic vein thrombosis are multifactorial. MRI and MRV confirm the diagnosis of SOVT. Despite urgent intervention devastating visual loss may occur.
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