Squamous cell carcinoma in an orthokeratinised odontogenic keratocyst

Clinicopathological differences between the typical parakeratinised odontogenic keratocyst (OKC) and the orthokeratinised variant are outlined. A case conforming to the histological criteria of an orthokeratinised OKC occurring in association with a squamous cell carcinoma is described and possible relationships between the two entities discussed.