[Antibiotherapy of severe ENT infections in children: peripharyngeal abscesses]

M Lorrot1, H Haas2, V Hentgen3

  • 1Groupe de pathologie infectieuse pédiatrique de la Société française de pédiatrie; Service de pédiatrie générale, hôpital Robert-Debré, 48 boulevard Sérurier, 75019 Paris, France; Inserm, CIE 5, Centre d'investigation clinique épidémiologie clinique, Essais cliniques, hôpital Robert-Debré, 48 boulevard Serurier, 75019 Paris, France; Université Paris-Diderot, Sorbonne Paris Cité, 5 rue Thomas-Mann, 75013 Paris, France.

Insights

Pediatric neck infections require specific antimicrobial therapy based on location and age. Initial treatment involves high-dose parenteral amoxicillin-clavulanate, transitioning to oral, for 10-14 days.

Area of Science:

  • Pediatric infectious diseases
  • Otolaryngology
  • Pharmacology

Context:

  • Neck infections in children present diverse clinical features and severity based on anatomical location and pediatric age groups.
  • In France, common pathogens include methicillin-sensitive Staphylococcus aureus, Streptococcus pyogenes, and anaerobic bacteria.

Purpose:

  • To outline the classification and clinical presentation of pediatric neck infections.
  • To define appropriate antimicrobial therapy for pediatric neck infections in France, considering local epidemiology.

Summary:

  • Pediatric neck infections are classified as peritonsillar, latero-, and retroparapharyngeal infections.
  • Recommended empiric antimicrobial therapy starts with high-dose parenteral amoxicillin-clavulanate (150 mg/kg/day), followed by oral amoxicillin-clavulanate (80 mg/kg/day).
  • The total treatment duration is recommended to be 10 to 14 days.

Impact:

  • Provides guidance for clinicians on managing pediatric neck infections.
  • Ensures appropriate and effective antimicrobial use, potentially reducing complications and resistance.
  • Contributes to standardized care protocols for pediatric head and neck infections.

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