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Updated: May 4, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
Published on: February 9, 2011
[Antibiotherapy of severe ENT infections in children: peripharyngeal abscesses]
M Lorrot1, H Haas2, V Hentgen3
1Groupe de pathologie infectieuse pédiatrique de la Société française de pédiatrie; Service de pédiatrie générale, hôpital Robert-Debré, 48 boulevard Sérurier, 75019 Paris, France; Inserm, CIE 5, Centre d'investigation clinique épidémiologie clinique, Essais cliniques, hôpital Robert-Debré, 48 boulevard Serurier, 75019 Paris, France; Université Paris-Diderot, Sorbonne Paris Cité, 5 rue Thomas-Mann, 75013 Paris, France.
Insights
Pediatric neck infections require specific antimicrobial therapy based on location and age. Initial treatment involves high-dose parenteral amoxicillin-clavulanate, transitioning to oral, for 10-14 days.
Area of Science:
- Pediatric infectious diseases
- Otolaryngology
- Pharmacology
Context:
- Neck infections in children present diverse clinical features and severity based on anatomical location and pediatric age groups.
- In France, common pathogens include methicillin-sensitive Staphylococcus aureus, Streptococcus pyogenes, and anaerobic bacteria.
Purpose:
- To outline the classification and clinical presentation of pediatric neck infections.
- To define appropriate antimicrobial therapy for pediatric neck infections in France, considering local epidemiology.
Summary:
- Pediatric neck infections are classified as peritonsillar, latero-, and retroparapharyngeal infections.
- Recommended empiric antimicrobial therapy starts with high-dose parenteral amoxicillin-clavulanate (150 mg/kg/day), followed by oral amoxicillin-clavulanate (80 mg/kg/day).
- The total treatment duration is recommended to be 10 to 14 days.
Impact:
- Provides guidance for clinicians on managing pediatric neck infections.
- Ensures appropriate and effective antimicrobial use, potentially reducing complications and resistance.
- Contributes to standardized care protocols for pediatric head and neck infections.
Abstract:
Neck infections in children are categorized as peritonsillar infections, latero and retroparapharyngeal infections. The clinical features and severity of these infections vary according to different pædiatric age groups, in relation to the location of the infection. In France, the antimicrobial therapy should consider meticillin sensitive S. aureus, Streptococcus pyogenes and anerobic bacteria. Empiric initial antimicrobial therapy consists in high doses of parenteral amoxicillin-clavulanate (150 mg/kg d. in 3-4 doses) during a few days then changed to oral amoxicillin-clavulanate (80 mg/kg/d). The total course of therapy should be 10 to 14 days.
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