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[Insulin treatment in children with type one diabetes]

J Beltrand1, J-J Robert1

  • 1Unité d'endocrinologie, gynécologie et diabétologie pédiatrique, hôpital universitaire Necker-Enfants-Malades, Paris, France; Faculté de médecine Paris-Descartes, Paris, France; Inserm U845, unité affiliation IMAGINE, Paris, France.

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|December 24, 2013
PubMed

Insights

Optimizing insulin therapy for children with diabetes focuses on mimicking natural insulin levels for better metabolic control. Modern insulin analogs and personalized dosing strategies, alongside proper education, are key to managing blood glucose effectively and minimizing hypoglycemia.

Area of Science:

  • Pediatric Endocrinology
  • Metabolic Disorders
  • Pharmacology

Context:

  • Insulin therapy is crucial for managing diabetes in children.
  • Physiological insulin replacement aims for optimal metabolic control.
  • Current treatments involve rapid and long-acting insulin analogs.

Purpose:

  • To outline the principles of insulin treatment in pediatric diabetes care.
  • To highlight the benefits of insulin analogs in glycemic control and hypoglycemia reduction.
  • To emphasize individualized dosing and administration strategies.

Summary:

  • Insulin treatment in all age groups should closely mimic physiological insulin replacement for optimal metabolic control.
  • Rapid and long-acting insulin analogs improve glycemic control and reduce hypoglycemia in children.
  • Insulin dosage requires individualization based on daily glucose patterns, basal needs, and mealtime requirements, necessitating regular review.
  • Administration devices must be pediatric-adapted, and all regimens require age-appropriate education for the child and family.

Impact:

  • Improved glycemic control and reduced hypoglycemia in pediatric diabetes patients.
  • Enhanced understanding of personalized insulin dosing strategies for children.
  • Guidance on selecting appropriate insulin administration devices and educational support for families.

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