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Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
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Cardiac manifestations of subarachnoid hemorrhage

A Ahmadian1, A Mizzi2, M Banasiak1

  • 1Department of Neurosurgery, University of South Florida, Tampa, Florida.

Heart, Lung and Vessels
|December 24, 2013
PubMed

Insights

Cardiac complications are common in subarachnoid hemorrhage patients. Myocardial infarction, especially with elevated troponin levels, significantly increases the risk of death in these patients.

Area of Science:

  • Neurology
  • Cardiology
  • Critical Care Medicine

Background:

  • Subarachnoid hemorrhage (SAH) can lead to various cardiac complications, including myocardial infarction and arrhythmias.
  • The clinical significance and prognostic impact of these cardiac events in SAH patients remain incompletely understood.

Purpose of the Study:

  • To determine the frequency of cardiac abnormalities in patients with aneurysmal subarachnoid hemorrhage.
  • To assess the influence of these cardiac complications on patient outcomes.

Main Methods:

  • Retrospective review of 617 patients with non-traumatic aneurysmal SAH.
  • Subgroup analysis of 87 patients who underwent cardiological evaluation, examining radiographic, clinical, and cardiac data.

Main Results:

  • Cardiac complications observed: myocardial infarction (47%), arrhythmia (63%), congestive heart failure (31%).
  • High World Federation of Neurosurgical Surgeons grade and troponin levels >1.0 mcg/L were associated with significantly increased mortality risk (33x and 10x, respectively).

Conclusions:

  • Myocardial infarction in SAH patients is linked to a tenfold increased risk of death.
  • Elevated troponin levels (>1.0 mcg/L) are a critical indicator of poor prognosis in SAH patients with cardiac events.
Abstract

Keywords:
MISAHTakotsubo stress cardiomyopathyarrhythmiacardiac outcomesintracranial aneurysmmyocardial Infarctionsubarachnoid hemorrhage

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