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Assessing Changes in Volatile General Anesthetic Sensitivity of Mice after Local or Systemic Pharmacological Intervention
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Molecular interactions between general anesthetics and the 5HT2B receptor

Felipe Matsunaga1, Lu Gao, Xi-Ping Huang

  • 1a Department of Anesthesiology and Critical Care , Perelman School of Medicine, University of Pennsylvania , 336 John Morgan Building, 3620 Hamilton Walk, Philadelphia , PA 19104 , USA.

Journal of Biomolecular Structure & Dynamics
|December 25, 2013
PubMed
Summary

General anesthetics propofol and isoflurane interact with serotonin 5-HT2B receptors. These findings suggest that serotonin receptors are potential targets for anesthetic drugs.

Keywords:
anestheticsisofluranepropofolserotonin receptor

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