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Proofreading

Proofreading

Proofreading

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Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore, it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
Errors During Replication are Corrected by the DNA Polymerase...

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Related Experiment Video

Updated: May 4, 2026

Denaturing Gradient Gel Electrophoresis DGGE

Denaturing Gradient Gel Electrophoresis DGGE

Published on: February 25, 2007

[Report of the editors, 2013].

J García Puig¹, G Gaspar Alonso-Vega², J J Ríos Blanco²

¹Editor Jefe, Revista Clínica Española.

Revista Clinica Espanola

|December 25, 2013

Summary

Revista Clínica Española enhanced its editorial processes in 2013, including English translations and faster decision times. The journal aims to improve its impact factor by reducing self-citations and increasing article visibility.

Keywords:

Biomedical journals Editors report Informe editores Revistas biomédicas Sociedad Española de Medicina Interna Spanish Society of Internal Medicine

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Last Updated: May 4, 2026

Denaturing Gradient Gel Electrophoresis DGGE

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Published on: May 21, 2008

Area of Science:

Medical publishing
Journal editorial management
Scientific communication

Context:

Revista Clínica Española (Rev Clin Esp) reports on its 2013 editorial activities and future objectives.
Key changes included English translations of abstracts and improved manuscript processing times.

Purpose:

To provide an overview of Revista Clínica Española's editorial performance in 2013.
To outline strategic initiatives for journal improvement in 2014.
To address challenges such as impact factor exclusion due to self-citations.

Summary:

Received 458 manuscripts, with an overall acceptance rate of 23.7% (11.8% for originals).
Reduced average editorial decision time to 20.3 days and time to online publication to 94.8 days.
Initiated English abstract translations and is working on digitizing back issues.

Impact:

Journal Citation Reports excluded Rev Clin Esp due to high self-citations; actions are underway to rectify this.
Manuscript citations to Rev Clin Esp articles increased from 19% in 2008 to 29% in 2012.
Ongoing efforts aim to enhance journal quality and international discoverability.